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Vertex Pharmaceuticals (VRTX): analysis and statistics

Return, volatility, Sharpe ratio and risk for Vertex Pharmaceuticals, a component of both the S&P 500 and the Nasdaq 100 in the Health Care sector. Data as of 2026-09-13.

Last close price$515.44
Sector (GICS)Health Care
Annualized return (3.0 yr)+14.22%
Total return over period+48.61%
Annualized volatility29.88%
Period volatility51.58%
Sharpe ratio0.34
Sortino ratio0.47
Max drawdown-29.07%
CVaR 95% (avg. loss, worst 5% of days)-4.10%
Correlation with the S&P 5000.26
Period range$343.00 – $557.96
Trading days analyzed751

Over the last 3.0 years, Vertex Pharmaceuticals (VRTX) has posted an annualized return of +14.22% with annual volatility of 29.88%, a Sharpe ratio of 0.34. Its worst stretch (max drawdown from a peak) was -29.07%. Its correlation with the S&P 500 is 0.26, which means it moves fairly independently of the index, useful for diversification.

These are historical, realized metrics, not projections: they describe how the stock behaved, not how it will behave going forward. To see how VRTX would fit inside an optimized portfolio alongside other stocks, try the optimizer.

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Is it part of the S&P 500?

Yes, Vertex Pharmaceuticals (VRTX) is of both the S&P 500 and the Nasdaq 100.

What is the Sharpe ratio? · How to optimize an investment portfolio

Information for educational purposes only. Not financial advice or a recommendation to buy or sell. Past performance does not guarantee future results.